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Faculty

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Hu Qinan
Research Assistant Professor

SELF-INTRODUCTION:

Dr. Qinan Hu is a Research Assistant Professor at SUSTech School of Medicine. He earned his Ph.D. degree at Cornell University in 2020. His research interests focus on investigation of tissue development and tumor precision medicine using system biology. His research areas include dissection of Drosophila development and disease models with high-resolution spatial transcriptomics, and development and application of single-cell multi-omic techniques in tumor cell drug response heterogeneity. His research has been published journals including Developmental Cell, PNAS, etc. He hosts one NSFC Young Scientists Fund.


EDUCATION:

2014-2020 Cornell University, Ph.D., majoring molecular biology/developmental biology

2010-2014 Peking University, B.S., majoring life sciences

WOKRING EXPERIENCE:

2020-2022 Southern University of Science and Technology, postdoctoral researcher                     

HONORS AND AWARDS:

2021 Shenzhen Overseas High-level Talents Award, Category C

2020 Southern University of Science and Technology, Presidential Postdoctoral Fellowship

2020 Cornell University,LPS BMCB Best Paper Award

2019 Cornell University,Graduate School Research Travel Grant

2018 Cornell University,George P. Hess Award

 

RESEARCH:

1.  Dissecting Drosophila development and disease models with high-resolution spatial transcriptomic technique Stereo-seq

2.  Development and application of single-cell damage quantification technique DISC-seq

3.  Resolving tumor cell drug response heterogeneity with single-cell multi-omic techniques


PUBLICATIONS:

1.  Wang, M.*, Hu, Q.*, Lv, T.*, Wang Y.*, Lan, Q.*, Tu, Z.*, Xiang, R.*, et al., 2022. High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae. Developmental Cell, 57(10), 1271-1283.e4

2.  Koreman, G.T.*, Hu, Q.*, Xu, Y.*, Zhang Z., Wang, B., Allen, S.E., Wolfner, M.F. and Han, C, 2021. Upgrading CRISPR/Cas9-mediated tissue-specific mutagenesis in Drosophila. Proceedings of the National Academy of Sciences, 118(14), e2014255118

3.  Hu, Q. and Wolfner, M.F., 2020. Regulation of calcium wave initiation during Drosophila egg activation. Molecular Reproduction and Development, 87(8), 880-886

4.  Hu, Q., Duncan, F.E., Nowakowski, A.B., Antipova, O.A., Woodruff, T.K., O’Halloran, T.V. and Wolfner, M.F., 2020. Zinc dynamics during Drosophila oocyte maturation and egg activation. iScience 23(7), 101275

5.  York-Andersen, A.H.*, Hu, Q.*, Wood, B. W., Wolfner, M.F. and Weil, T.T., 2019. A calcium-mediated actin redistribution at egg activation in Drosophila. Molecular Reproduction and Development, 87(2), 293-304

6.  Hu, Q. and Wolfner, M.F., 2019. The Drosophila Trpm channel mediates calcium influx during egg activation. Proceedings of the National Academy of Sciences, 116(38), pp.18994-19000


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