師資
研究領(lǐng)域
目前，課題組主要研究兩大領(lǐng)域:
(1) 研究細胞與發(fā)育生物學(xué)相關(guān)課題:主要利用人體細胞及秀麗隱桿線蟲研究調(diào)控細胞分裂、細胞極性及細胞粘附的分子機理及相關(guān)器官發(fā)育機制。
(2) 開發(fā)熒光納米探針應(yīng)用于癌癥治療及檢測：通過與化學(xué)領(lǐng)域的課題組合作，設(shè)計并合成熒光納米探針，然后利用人體細胞及小鼠模型進行各類治療及檢測癌細胞的應(yīng)用性研究。
工作經(jīng)歷
2020年至今，公共分析測試中心，副主任；
2013年至2020年 南方科技大學(xué)，生物系，副教授；
2012年 香港科技大學(xué)，博士后；
2007年至2012年 美國芝加哥大學(xué)分子遺存及細胞生物學(xué)系，博士后。
學(xué)習(xí)經(jīng)歷
2007，香港中文大學(xué)生物學(xué)博士學(xué)位；
2003，香港中文大學(xué)生物技術(shù)碩士學(xué)位；
2001，香港中文大學(xué)生物技術(shù)學(xué)士學(xué)位。
代表文章
1. Li L, Wang S, Lan H, Gong G, Zhu Y, Tse YC#, Wong KM#. Rhodol Derivatives as Selective Fluorescent Probes for the Detection of HgII Ions and the Bioimaging of Hypochlorous Acid. ChemistryOpen 7: 136-143.
2. Li L, Wang C, Wu J, Tse YC#, Cai YP, Wong KM#. (2016) A Molecular Chameleon with Fluorescein and Rhodamine Spectroscopic Behaviors. Inorganic Chemistry 55: 205-213.
3. Basant A, Lekomtsev S, Tse YC, Zhang D, Longhini KM, Petronczki M, Glotzer M. (2015) Aurora B kinase promotes cytokinesis by inducing centralspindlin oligomers that associate with the plasma membrane. Developmental Cell 33: 204-215
4. Tse YC*, Werner ME, Longhini MK, Labbe JC, Goldstein B, Glotzer M. (2012) RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4. Molecular Biology of the Cell 23: 4023-4031.
5. Tse YC*, Wang J, Jiang L. (2012) Multivesicular bodies in developing tobacco seed and mung bean are functionally equivalent. Plant Signaling & Behavior 7:1-4.
6. Tse YC*, Piekny A, Glotzer M. (2011) Anillin promotes astral microtubule-directed cortical myosin polarization. Molecular Biology of the Cell 22:3165-3175.
7. Wang J, Tse YC, Hinz G, Robinson DG, Jiang L. (2011) Storage globulins pass through the Golgi apparatus and multivesicular bodies in the absence of dense vesicle formation during early stages of cotyledon development in mung bean. Journal of Experimental Botany 63:1367-1380.
8. Afshar K, Werner ME^, Tse YC^, Glotzer M, G?nczy P. (2010) Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C. elegans embryos. Development 137:237-47. (^ these authors contributed equally to this work.)
9. Wang H, Tse YC, Law AH, Sun SS, Sun YB, Xu ZF, Hillmer S, Robinson DG, Jiang L. (2010) Vacuolar sorting receptors (VSRs) and secretory carrier membrane proteins (SCAMPs) are essential for pollen tube growth. The Plant Journal 61:826-838.
10. Tse YC*, Lam SK, Jiang L. (2009) Organelle identification and characterization in plant cells: Using a combinational approach of confocal immunofluorescence and electron microscope. Journal of Plant Biology 52:1-9.
11. Lam SK, Cai Y, Tse YC, Wang J, Law AH, Pimpl P, Chan HY, Xia J, Jiang L. (2009) BFA-induced compartments from the Golgi apparatus and trans-Golgi network/early endosome are distinct in plant cells. The Plant Journal 60:865-881.
12. Lam SK, Tse YC, Miao Y, Li HY, Wang J, Lo SW, Jiang L. (2007) Molecular characterization of plant prevacuolar and endosomal compartments. Journal of Integrative Plant Biology 49:1119-1128.
13. Lam SK, Tse YC, Robinson DG and Jiang L. (2007) Tracking down the elusive early endosome. Trends in Plant Science 12: 497-505.
14. Tse YC*, Lam SK and Jiang L. (2007) Enigmatic Brefeldin A. Plant Signaling & Behavior. Plant Physiology 2: 199-202.
15. Tse YC*, Lo SW, Hillmer S, Dupree P and Jiang L. (2006) Dynamic response of prevacuolar compartments to Brefeldin A in plant cells. Plant Physiology 142:1442-1459.
16. Oliviusson P, Heinzerling L, Hillmer S, Hinz G, Tse YC, Jiang L and Robinson DG. (2006) Plant retromer: identification, localization to the prevacuolar compartment and microvesicles, and preliminary evidence for an interaction with vacuolar sorting receptors. Plant Cell 18:1239-1252.
17. Tse YC*, Mo BX* and Jiang L. (2006) Plant prevacuolar/endosomal compartments. International Review of Cytology 253:95-129. (* these authors contributed equally to this work.)
18. Fung KL, Yim YF, Tse YC, Miao Y, Sun SSM and Jiang L. (2005) Targeting and processing of membrane-anchored YFP fusion proteins to protein storage vacuole in transgenic tobacco seeds. Seed Science Research 15:361-364.
19. Lam SK, Tse YC, Jiang L, Oliviusson P, Heinzerling L and Robinson DG. (2005) Plant prevacuolar compartments and endocytosis. In “Plant Endocytosis” Samaj, J., Baluska, F. and Menzel, D. (eds) Plant Cell Monographs 1:37-61.
20. Tse YC*, Mo B, Zhao M, Robinson DG, Hillmer S, Lo SW and Jiang L. (2004) Identification of multivescular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells. Plant Cell 16:672-693.
21. Jin JB, Bae H, Kim SJ, Jin YH, Goh CH, Kim DH, Lee YJ, Tse YC, Jiang L and Hwang I. (2003) The Arabidopsis dynamin-like proteins ADL1C and ADU1E play a critical role in mitochondrial morphogenesis. Plant Cell 15:2357-2369.
22. Mo B, Tse YC and Jiang L. (2003) Organelle identification and proteomics in plant cells. Trends in Biotechnology 21:331-332.
23. Li YB, Rogers SW, Tse YC, Lo SW, Sun SSM., Jauh GY and Jiang L. (2002) BP-80 and homologs are concentrated on post-Golgi, probable lytic prevacuolar compartments. Plant & Cell Physiology 43:726-742.
24. Lee SM, Li ML, Tse YC, Leung SC, Lee MM, Tsui SK, Fung KP, Lee CY, Waye MM. (2002) Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. Life Science. 71:2267-2277.