師資
個(gè)人簡(jiǎn)介
郭瓊玉，副教授，博士生導(dǎo)師。長(zhǎng)期注重于高分子生物材料在轉(zhuǎn)化醫(yī)學(xué)方向的研發(fā)，將其應(yīng)用于多個(gè)具有挑戰(zhàn)性的生物醫(yī)學(xué)課題，在可移植人工角膜、介入栓塞材料、長(zhǎng)效藥物控釋、記憶性納米材料以及細(xì)胞調(diào)控等領(lǐng)域里取得了突出的研究成果。郭瓊玉教授是深圳市海外高層次人才“孔雀計(jì)劃”B類獲得者，發(fā)表學(xué)術(shù)論文>40篇，被引用>1200次，申請(qǐng)專利15項(xiàng)，授權(quán)11項(xiàng)，其中可移植人工角膜和形狀記憶微納材料的研究成果在全球提交了多項(xiàng)專利申請(qǐng)，已經(jīng)獲得包括中國(guó)、美國(guó)、日本和歐洲等多個(gè)國(guó)家的專利授權(quán)；撰寫專著和章節(jié)2部；現(xiàn)任中國(guó)醫(yī)師協(xié)會(huì)介入醫(yī)師分會(huì)第三屆委員會(huì)介入醫(yī)學(xué)工程與生物技術(shù)學(xué)組委員、廣東省生物醫(yī)學(xué)工程學(xué)會(huì)智能介入醫(yī)學(xué)分會(huì)常務(wù)委員、深圳市生物醫(yī)學(xué)工程學(xué)會(huì)生物醫(yī)學(xué)材料專業(yè)委員會(huì)常委。
教育背景
2004年-2010年 美國(guó)凱斯西儲(chǔ)大學(xué)高分子工程 博士
1999年-2004年 中國(guó)科技大學(xué)高分子工程 學(xué)士
工作經(jīng)歷
2024年5月-至今 南方科技大學(xué)生物醫(yī)學(xué)工程系 副教授
2017年-2024年5月 南方科技大學(xué)生物醫(yī)學(xué)工程系 助理教授
2016年-2017年 美國(guó)里海大學(xué)生物工程 研究員
2009年-2016年 美國(guó)約翰霍普金斯大學(xué)生物醫(yī)學(xué)工程 博士后
獲獎(jiǎng)及榮譽(yù)
2010-2013 美國(guó)關(guān)節(jié)炎基金博士后獎(jiǎng)學(xué)金
研究興趣
郭瓊玉博士主要研究方向是開發(fā)納米至微米尺度新型形狀記憶性藥物釋放體系用于腫瘤治療和組織再生，其目標(biāo)為從材料、細(xì)胞、動(dòng)物實(shí)驗(yàn)多個(gè)層面為解決具體的臨床問題設(shè)計(jì)一系列智能材料。
代表論文
1. Q. Guo, D. Miller, H. An, H. Wang, J. Lopez, D. Lough, L. He and A. Kumar, “Controlled heat stress promotes myofibrillogenesis during myogenesis,” PLoS ONE 11(11) (2016) e0166294.
2. S. Majumdar, Q. Guo, M. Garza-Madrid, X. Calderon-Colon, D. Duan, P. Carbajal, O. Schein, M. Trexler, and J. Elisseeff, “Influence of collagen source on fibrillar architecture and properties of vitrified collagen membranes”, J. Biomed. Mater. Res. Part B. 104B (2016) 300-307.
3. Q Guo, J.P. Mather, P. Yang, M. Boden, and P.T. Mather, “Fabrication of polymeric coatings with controlled microtopographies using an electrospraying technique,” PLoS ONE 10(6) (2015) e0129960.
4. S. Yang,# Q. Guo,# L. Shores, A. Aly, M. Ramakrishnan, G.-H. Kim, Q. Lu, L. Su, G. Zhao, J.H. Elisseeff, “Use of a chondroitin sulfate bioadhesive to enhance integration of bioglass particles for repairing critical-size bone defects,” J. Biomed. Mater. Res. Part A. 103A (2015) 235-242. (#= Co-first author)
5. Q. Guo, J.M. Phillip, S. Majumdar, P. Wu, J. Chen, X. Calderón-Colón, O. Schein, B.J. Smith, M.M. Trexler, D. Wirtz, and J.H. Elisseeff, “Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair,” Biomaterials 34 (2013) 9365-9372.
6. Q. Guo,# X. Wang,# M.W. Tibbitt, K.S. Anseth, D.J. Montell, and J.H. Elisseeff, “Light activated cell migration in synthetic extracellular matrices,” Biomaterials 33 (2012) 8040-8046. (#= Co-first author)
7. Q. Guo, A. Aly, O. Schein, M.M. Trexler, and J.H. Elisseeff, “Moxifloxacin in situ gelling microparticles-bioadhesive delivery system,” Results in Pharma. Sciences 2 (2012) 66-71.
8. A.T. Hillel, S. Unterman, Z. Nahas, B. Reid, J.M. Coburn, J. Axelman, J.J. Chae, Q. Guo, R. Trow, A. Thomas, Z. Hou, S. Lichtsteiner, D. Sutton, C. Matheson, P. Walker, N. David, S. Mori, J.M. Taube, and J.H. Elisseeff, “Photoactivated composite biomaterial for soft tissue restoration in rodents and in human,” Sci. Tranl. Med. 3, 93ra67 (2011) 1-12.
9. Q. Guo, P.T. Knight, J. Wu, and P.T. Mather, “Blends of paclitaxel with POSS-based biodegradable polyurethanes: morphology, miscibility, and specific interactions,” Macromolecules 43 (2010) 4991-4999.
10. Q. Guo, P.T. Knight, and P.T. Mather, “Tailored drug release from biodegradable stent coatings based on hybrid polyurethanes,” J. Control. Release 137 (2009) 224-233.
著書章節(jié)
1. Q. Guo, and J.H. Elisseeff, Cartilage Tissue Engineering, in: A. Atala, R. Lanza, J.A. Thomson, R. Nerem (Eds.), Principles of Regenerative Medicine, 2nd Ed, Elsevier, 2011, pp. 981-995.
專利申請(qǐng)
1. Q. Guo, J. Green, R.A. Meyer, C.J. Bishop, A. Kumar, and G.L. Semenza, “Shape memory particles for biomedical uses,” Patent application (WO2016164458A1) filed on April 6, 2016.
2. A. Kumar, D. Lough, C. Madsen, and Q. Guo, “Bone healing, angiogenesis-promoting and vasculogenesis-producing system,” Patent application (WO2016172004) filed on April 15, 2016.
3. J.H. Elisseeff, Q. Guo, and S. Majumdar, “Compositions comprising cyclodextrin incorporated collagen matrices for use in biomedical applications,” Patent application (US20170043021A1) filed on September 10, 2015.
4. J.H. Elisseeff, Q. Guo, S. Majumdar, and A. Singh, “Cornea mimetic biomaterials: vitrified collagen-cyclodextrin implants,” Patent Application (WO2016171745A1) filed on April 24, 2015.
5. M.M. Trexler, J.H. Elisseeff, D.G. Mulreany, Q. Guo, J.L. Breidenich, J.P. Maranchi, J.L. Graham, J.B. Patrone, M.W. Patchan, and X. Calderon-Colon, “Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof,” Approved by USPTO on April 19, 2016. Patent #US9314531B2.