陶麗芝，南方科技大學(xué)化學(xué)系副教授、博士生導(dǎo)師、課題組長。2011年于清華大學(xué)化學(xué)系獲碩士學(xué)位 (導(dǎo)師：徐柏慶教授)，研究方向為固體酸堿多相催化化學(xué)。之后前往美國加州大學(xué)戴維斯分校 (University of California, Davis) 全球著名電子順磁共振光譜 (Electron Paramagnetic Resonance, EPR) 實驗室攻讀博士學(xué)位 (導(dǎo)師：R. David Britt 教授; William H. Casey 教授) ，研究方向為運用電子順磁共振光譜研究多銅氧化酶催化反應(yīng)的分子機制。2016年獲得博士學(xué)位后留校從事博士后研究工作，將研究拓展至多種紛繁復(fù)雜的化學(xué)以及生物化學(xué)體系當(dāng)中；運用電子順磁共振光譜EPR對這些體系中的關(guān)鍵順磁物種進(jìn)行三維結(jié)構(gòu)鑒定和解析，獲得了原子、分子層面上反應(yīng)機理及構(gòu)效關(guān)系的認(rèn)識和理解。迄今為止，在領(lǐng)域內(nèi)頂級國際學(xué)術(shù)刊物 (J. Am. Chem. Soc., Nature Chem., Nature Rev. Chem.等) 發(fā)表論文40余篇。2021年入選海外高層次人才計劃青年項目，2022年7月加入南方科技大學(xué)化學(xué)系。
研究方向：
1. 先進(jìn)電子順磁共振光譜Advanced Electron Paramagnetic Resonance, EPR；
2. 金屬蛋白酶催化反應(yīng)機理研究；
3. 金屬有機、表面多相催化化學(xué)反應(yīng)分子機制。
代表性論文：
[10] Y. Zhang#, L. Tao# (co-first author), T. Woods, R. D. Britt and T. B. Rauchfuss, “Organometallic Fe2(μ-SH)2(CO)4(CN)2 cluster allows the biosynthesis of the [FeFe]-hydrogenase with only the HydF maturase”, J. Am. Chem. Soc., 2022, 144, 1534-1538.
[9] R. D. Britt*, G. Rao* and L. Tao*, “Bioassembly of complex iron–sulfur enzymes: hydrogenases and nitrogenases”, Nat. Rev. Chem., 2020, 4, 542-549.
[8] L. Tao, S. A. Pattenaude, S. Joshi, T. P. Begley, T. B. Rauchfuss and R. D. Britt, “Radical SAM enzyme HydE generates adenosylated Fe(I) intermediates en route to the [FeFe]-hydrogenase catalytic H-cluster”, J. Am. Chem. Soc., 2020, 142, 10841-10848.
[7] L. Tao, T. Y. Lai, P. P. Power and R. D. Britt, “Germanium hydride radical trapped during the photolysis/thermolysis of diarylgermylene”, Inorg. Chem., 2019, 58, 15034-15038.
[6] L. Tao, W. Zhu, J. P. Klinman and R. D. Britt, “Electron paramagnetic resonance spectroscopic identification of the Fe–S clusters in the SPASM domain-containing radical SAM enzyme PqqE”, Biochemistry, 2019, 58, 5173-5187.
[5] L. Tao, T. A. Stich, C. J. Fugate, J. T. Jarrett and R. D. Britt, “EPR-derived structure of a paramagnetic intermediate generated by biotin synthase BioB”, J. Am. Chem. Soc., 2018, 140, 12947-12963.
[4] L. Tao, T. A. Stich, W. H. Casey, R. D. Britt, et al., “Copper binding sites in the manganese-oxidizing Mnx protein complex investigated by electron paramagnetic resonance spectroscopy”, J. Am. Chem. Soc., 2017, 139, 8868-8877.
[3] L. Tao, T. A. Stich, W. H. Casey, R. D. Britt, et al., “Mn(II) binding and subsequent oxidation by the multicopper oxidase MnxG investigated by electron paramagnetic resonance spectroscopy”, J. Am. Chem. Soc., 2015, 137, 10563-10575.
[2] L. Tao, S.-H. Chai, H.-P. Wang, B. Yan, Y. Liang and B.-Q. Xu, “Comparison of gas-phase dehydration of propane polyols over solid acid–base catalysts”, Catal. Today, 2014, 234, 237-244.
[1] L. Tao, B. Yan, Y. Liang and B.-Q. Xu, “Sustainable production of acrolein: catalytic performance of hydrated tantalum oxides for gas-phase dehydration of glycerol”, Green Chem., 2013, 15, 696-705.
