師資
吳長鋒教授，入選國家青年人才、科技創(chuàng)新領軍人才，先后獲得國家自然科學基金優(yōu)秀青年項目、國家自然科學基金重點項目（2項）、國家重點研發(fā)計劃、深圳市孔雀團隊等項目資助。研究方向為光學分子探針和生物成像技術，迄今發(fā)表SCI 論文200余篇，SCI引用15000多次，H因子63，近五年連續(xù)入選“愛思唯爾”中國高被引學者榜單。擔任南科大生物醫(yī)學工程系教學副主任，講授《生物醫(yī)學光學》、《生物醫(yī)學光學實驗》、《生物醫(yī)學工程概論》、《高級顯微學》等課程。獲得深圳市“先進教育工作者”、南方科技大學“杰出教學獎”。
實驗室主頁：http://wulab.bme.sustech.edu.cn/
研究方向：
1）光學分子探針與超分辨光學成像
2）近紅外熒光分子和深層組織成像
3）生物光學傳感器及健康監(jiān)測系統(tǒng)
教育背景
1994-1998 齊魯工業(yè)大學材料科學與工程學院 本科
1998-2001 吉林大學材料科學與工程學院 碩士
2001-2004 中科院長春光機與物理研究所 凝聚態(tài)物理博士
2005-2008 美國克萊姆森大學化學系 物理化學博士
工作經(jīng)歷
2004-2005 美國克萊姆森大學物理系 博士后
2008-2011 美國華盛頓大學化學系 博士后
2011-2016 吉林大學電子科學與工程學院 教授
2016-至今 南方科技大學生物醫(yī)學工程系 教授
項目負責人
2023-2027 國家自然科學基金重點項目 “活體深層腦組織近紅外二區(qū)超分辨成像研究”
2020-2025 國家重點研發(fā)計劃課題 “惡性消化系腫瘤特異性分子探針的精確核素標記與方法學研究”
2019-2024 深圳市孔雀團隊項目 “腦瘤靶向探針及診療技術”
2014-2018 國家自然科學基金重點項目 “開關/閃爍可控聚合物量子點的設計制備及納米分辨動態(tài)光學成像研究”
2013-2015 國家自然科學優(yōu)秀青年基金項目 “生物醫(yī)學光子學”
發(fā)表論文
1. Mi, F.; Liu, Z.; Wang, X.; Wang, Y.; Yang, J.; Wang, Z.; Yin, S.; Fang, X.; Shu, P.*; Zhang, X.*; Wu, C.*, Deep Red Light Driven Hydrogen Evolution by Heterojunction Polymer Dots for Diabetic Wound Healing. Angewandte Chemie International Edition, 2024, 63(29), e202402133.
2. Li, D.; Shi, T.; Xiao, Y.; Wu C.*, Sensorless Adaptive Optics in the Second Near-Infrared Window for Deep Vascular Imaging In Vivo. Optics Letters, 2024, 49(14), 4002-4005.
3. Chen, D.; Qi, W.; Liu, Y.; Yang, Y.; Shi, T.; Wang, Y.; Fang, X.; Wang, Y.; Xi, L.*; Wu, C.*, Near-Infrared II Semiconducting Polymer Dots: Chain Packing Modulation and High-Contrast Vascular Imaging in Deep Tissues. ACS Nano, 2023, 17 (17), 17082-17094.
4. Liu, J.; Liu, Z.; Mi, F.; Yao, Z.; Fang, X.; Wang, Y.; Zhao, Z.*; Wu, C.*, Fluorescence Lifetime Multiplex Imaging in Expansion Microscopy with Tunable Donor–Acceptor Polymer Dots. Chemical & Biomedical Imaging, 2023, 1 (6), 550–557.
5. Wang, C.; Sun, Y.; Huang, S.; Wei, Z.; Tan, J.; Wu, C.*; Chen, Q.*; Zhang X.*, Self-Immolative Photosensitizers for Self-Reported Cancer Phototheranostics. Journal of the American Chemical Society, 2023, 145(24), 13099-13113.
6. Zhang, Z.; Li, W.; Liu, Y.; Fang, X.; Wu, C.*, Semiconducting Polymer Nanoparticles in the Second Near-Infrared Region for Biomedical Imaging and Therapy. Advanced Optical Materials, 2023, 11(11), 2202052.
7. Liu, S.; Liu, Y.; Zhang, Z.; Wang, X.; Yang, Y.; Sun, K.; Yu, J.; Chiu, D.T.; Wu, C.*, Near-Infrared Optical Transducer for Dynamic Imaging of Cerebrospinal Fluid Glucose in Brain Tumor. Analytical Chemistry, 2022, 94, 14265–14272.
8. Liu, J.; Fang, X.; Zhang, Z.; Liu, Z.; Liu, J.; Sun, K.; Yuan, Z.; Yu, J.; Chiu, D.T.; Wu, C.*, Long-Term In Vivo Glucose Monitoring by Polymer-Dot Transducer in an Injectable Hydrogel Implant. Analytical Chemistry, 2022, 94(4), 2195–2203.
9. Ao, J.; Fang, X.; Mao, X.; Ling, J.; Kang, H.; Park, S.; Wu, C.*, Ji, M.*, Switchable Stimulated Raman Scattering Microscopy with Photochromic Vibrational Probes. Nature Communications, 2021, 12(1), 3089.
10. Liu, J.; Fang, X.; Liu, Z.; Li, R.; Yang, Y.; Sun, Y.; Zhao, Z.; Wu, C.*, Expansion Microscopy with Multifunctional Polymer Dots. Advanced Materials, 2021,33(25), 2007854.
11. Chen, D.; Liu, Y.; Zhang, Z.; Liu, Z.; Fang, X.; He, S.; Wu, C.*, NIR-II Fluorescence Imaging Reveals Bone Marrow Retention of Small Polymer Nanoparticles. Nano Letters, 2021, 21(1) :798–805
12. Liu, Y.; Liu, J.; Chen, D.; Wang, X.; Zhang, Z.; Yang, Y.; Jiang, L.; Qi, W.; Ye, Z.; He, S.; Liu, Q.; Xi, L.; Zou, Y.*; Wu, C.*, Fluorination Enhances NIR‐II Fluorescence of Polymer Dots for Quantitative Brain Tumor Imaging. Angewandte Chemie International Edition, 2020, 59 (47): 21049-21057.
13. Chen, H.; Wang, F.; Liu, M.; Qian, M.; Men, X.; Yao, C.; Xi, L.; Qin, W.; Qin, G.*; Wu, C.*, Near-Infrared Broadband Polymer-Dot Modulator with High Optical Nonlinearity for Ultrafast Pulsed Lasers. Laser & Photonics Reviews, 2019, 13(2), 1800326.
14. Sun, K.; Yang, Y.; Zhou, H.; Yin, S.; Qin, W.; Yu, J.; Chiu, D.T.; Yuan, Z.; Zhang, X.; Wu, C.*, Ultrabright Polymer-Dot Transducer Enabled Wireless Glucose Monitoring via a Smartphone. ACS Nano, 2018, 12 (6), 5176–5184
15. Chang, K.; Liu, Z.; Fang, X.; Chen, H.; Men, X.; Yuan, Y.; Sun, K.; Zhang, X.; Yuan, Z.; Wu, C.*, Enhanced Phototherapy by Nanoparticle-Enzyme via Generation and Photolysis of Hydrogen Peroxide. Nano Letters, 2017, 17 (7), 4323-4329.
16. Wu, C.; Chiu, D. T., Highly Fluorescent Semiconducting Polymer Dots for Biology and Medicine. Angewandte Chemie International Edition, 2013, 52 (11), 3086-3109.
17. Wu, C.; Hansen, S. J.; Hou, Q.; Yu, J.; Zeigler, M.; Jin, Y.; Burnham, D. R.; McNeill, J. D.; Olson, J. M.; Chiu, D. T., Design of Highly Emissive Polymer Dot Bioconjugates for In Vivo Tumor Targeting. Angewandte Chemie International Edition, 2011, 50 (15), 3430-3434.
18. Wu, C.; Schneider, T.; Zeigler, M.; Yu, J.; Schiro, P. G.; Burnham, D. R.; McNeill, J. D.; Chiu, D. T., Bioconjugation of Ultrabright Semiconducting Polymer Dots for Specific Cellular Targeting. Journal of American Chemical Society, 2010, 132 (43), 15410-15417.
19. Wu, C.; Jin, Y.; Schneider, T.; Burnham, D. R.; Smith, P. B.; Chiu, D. T., Ultrabright and Bioorthogonal Labeling of Cellular Targets Using Semiconducting Polymer Dots and Click Chemistry. Angewandte Chemie International Edition, 2010, 49 (49), 9436-9440.
20. Wu, C.; Bull, B.; Christensen, K.; McNeill, J., Ratiometric Single‐Nanoparticle Oxygen Sensors for Biological Imaging. Angewandte Chemie International Edition, 2009, 48 (15), 2741-2745.
21. Wu, C.; Zheng, Y.; Szymanski, C.; McNeill, J., Energy Ttransfer in a Nanoscale Multichromophoric System: Fluorescent Dye-Doped Conjugated Polymer Nanoparticles. Journal of Physical Chemistry C, 2008, 112(6), 1772-1781.
22. Wu, C.; Bull, B.; Szymanski, C.; Christensen, K.; McNeill, J., Multicolor Conjugated Polymer Dots for Biological Fluorescence Imaging. ACS Nano, 2008, 2 (11), 2415-2423.
23. Wu, C.; Szymanski, C.; Cain, Z.; McNeill, J., Conjugated Polymer Dots for Multiphoton Fluorescence Imaging. Journal of American Chemical Society, 2007, 129 (43), 12904-12905.
24. Wu, C.; Peng, H.; Jiang, Y.; McNeill, J., Energy Transfer Mediated Fluorescence from Blended Conjugated Polymer Nanoparticles. Journal of Physical Chemistry B, 2006, 110(29), 14148-14154.
25. Wu, C.; Szymanski, C.; McNeill, J., Preparation and Encapsulation of Highly Fluorescent Conjugated Polymer Nanoparticles. Langmuir, 2006, 22(7), 2956-2960.